The metabolism of orotic acid in aerobic bacteria.
نویسندگان
چکیده
cocci (Rogers, lW), Laetobaciuus cas& (Chattaway, lW), and Laclobaeiuus bulgcrricus, strain 09 (Wieland et d., 1950; Huff et d., 1950). Further studiea with L. bulgaricw, strain 09 have revealed that ureidosuccinic acid partially replacea that orotic acid ia also a nucleic acid pyrimidine a growth factor for one of the group C streptoprecursor in mammdim tissues. Studiea of orotic acid synthwia and breakdown with e n w e preparationa from an anaerobic bacterium, Zynobacterium oroticum, have indicated the following pathway (Lieberman and Komberg, 1953a; 1954, in preparutiun) :
منابع مشابه
Influence of ad Libitum Feeding of Piglets With Bacillus Subtilis Fermented Liquid Feed on Gut Flora, Luminal Contents and Health
Some scholars caution that long-term ad libitum feeding with probiotic fermented food poses potential health risks to baby animals. We conducted a feeding experiment to investigate the influence of ad libitum feeding of pre-and post-weaned piglets with a Bacillus subtilis fermented diet on the gut microbiome, gut metabolomic profiles, bile acid metabolism, proinflammatory cytokines and faecal c...
متن کاملEffect of 6-azauridine on plasma cell tumors of mice: correlation of antitumor effect with inhibition of orotic acid metabolism.
This investigation was undertaken to correlate the antineoplastic effects of 6-azauridine (AzUR) with the activity of orotic acid metabolism and its inhibition in vitro by AzUR in a series of plasma cell tumors of mice. Although AzUR suppressed tumor growth only moderately and to widely different degrees in different tumors, its antitumor effects in vivo appeared to follow its inhibition of oro...
متن کاملOrotic acid excretion and arginine metabolism.
The urinary excretion of orotic acid, an intermediate in the pyrimidine biosynthetic pathway, is markedly increased in many inborn errors of the urea cycle and in a number of other disorders involving arginine metabolism. Carbamoyl phosphate, which accumulates within hepatic mitochondria in patients with ornithine transcarbamoylase deficiency, can diffuse to the cytosol and enter the pyrimidine...
متن کاملEffect of Supplemental Ascorbic Acid on the Aerobic Capacity in Children
Introduction: ascorbic acid is a water-soluble vitamin solved in water that acts as a helper of some the enzymes in the reactions of energy metabolism. Thus, the study aims to investigate the use of supplemental ascorbic acid on the aerobic and anaerobic capacity of the children.Methodology: Participants of this quasi-experimental study were 18 children in Esfahan who were randomly selected and...
متن کاملBeneficial effect of orotic acid upon galactose metabolism of erythrocytes from congenital galactosemia.
In our preliminary report,,) we described that an oral administration of orotic acid to galactosemic patients resulted in a remarkable decrease of urinary galactose and in an improvement of galactose tolerance curve in addition to a noticeable improvement of clinical symptoms and signs of the patients. In this paper, the effect of orotic acid on galactose metabolism investigated in erythrocytes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of bacteriology
دوره 69 3 شماره
صفحات -
تاریخ انتشار 1955